Abstract

A 50-year-old Asian man with a history of a kidney transplant presented with a painless enlarging lesion on his right lower eyelid that had been growing for two years. Biopsy revealed a low-grade neoplasm with cribiform architecture and mucin production, and subsequent immunohistochemistry was suggestive of Endocrine Mucin-Producing Sweat Gland Carcinoma (EMPSGC). This case highlights the importance of a high index of suspicion for malignancy in immunocompromised patients with non-resolving lesions, and the need for regular skin checks.

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