Abstract

Brown tumor is a rare nonneoplastic focal giant cell lesion that occurs in hyperparathyroidism patients with a prevalence rate of 0.1% in jaws. We report an extremely rare case of brown tumor in mandible of a 40-year-old female patient that presented as the first clinical manifestation of hyperparathyroidism. Dentist played a pivotal role in the present case by the early diagnosis of lesion and its intervention.

Highlights

  • Hyperparathyroidism (HPT) is an endocrine disorder occurring due to increased secretion of paratharmone resulting in a complex of clinical, anatomical, and biochemical alterations [1]

  • HPT is categorized into 4 types: primary HPT is caused by parathyroid adenomas (85%), hyperplasias (10%), and carcinomas (5%)

  • We report a rare case of brown tumor occurring in mandible of a 40-year-old female patient that was the first clinical manifestation and presented as a multilocular radiolucency, which on further biochemical assessment confirmed the diagnosis of adenoma of parathyroid

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Summary

Introduction

Hyperparathyroidism (HPT) is an endocrine disorder occurring due to increased secretion of paratharmone resulting in a complex of clinical, anatomical, and biochemical alterations [1]. Brown tumor is mostly asymptomatic, but occasionally it may present as a painful exophytic mass [1] It appears as a unilocular or multilocular lesion with an irregular periphery. We report a rare case of brown tumor occurring in mandible of a 40-year-old female patient that was the first clinical manifestation and presented as a multilocular radiolucency, which on further biochemical assessment confirmed the diagnosis of adenoma of parathyroid. Along with this case report other giant cell mimickers of oral cavity are discussed

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