Abstract
An electrochemiluminescence (ECL) aptasensor based on poly(ethylenimine) functionalized nitrogen-doped carbon nanodots (NCDs@PEI) composite as co-reactant, and Ru(bpy)32+ nanosheets (RuNSs) as luminophor was constructed for the specific analysis of bisphenol A (BPA). On account of the double improvement functions of NCDs and PEI on RuNSs, the as-developed aptasensor exhibited superior ECL properties. In order to further enhance the selectivity of the RuNSs-NCDs@PEI system for BPA detection, we innovatively introduced the BPA aptamer to construct a novel ECL aptasensor. Compared with that without aptamer and with random DNA, the constructed aptasensor performed higher specificity for BPA determination under the interference of structural analogues. The as-prepared ECL aptasensor exhibited a wide linear range of 1.0 × 10−10 - 1.0 × 10−4 mol L−1, and a relatively low detection limit of 3.3 × 10−11 mol L−1 for BPA detection with good stability and repeatability. Finally, when the ECL aptasensor made use of BPA analysis in water samples, the obtained results were confirmed by high performance liquid chromatography-ultraviolet spectrum (HPLC-UV) method, verifying its good accuracy. The novel aptasensor provided a new sensing platform for BPA in water samples.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
