Abstract
Abstract A simple method for the one-pot, three-component Biginelli condensation reaction of 5-chloro/phenoxyl-3-methyl-1-phenyl-4-formylpyrazole, a 1,3-dicarbonyl compound and urea or thiourea is described, employing Magnesium perchlorate [Mg(ClO 4 ) 2 ] as an efficient catalyst under ultrasound irradiation. A novel series of 4-substituted pyrazolyl-3,4-dihydropyrimidin-2(1H)-(thio)ones have been synthesized in moderate yields. The catalyst exhibited remarkable reactivity and can be recycled.
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call