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https://doi.org/10.1016/s0040-4020(98)01101-6
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Cite Journal: Tetrahedron |  Publication Date: Jan 1, 1999 |
 Citations: 13 |
Affiliation: Iowa State University
A synthesis of 4-aryl kainic acid analogs was achieved using a highly stereoselective Michael addition reaction of dimethyl 2-oxoglutarate with a nitrostyrene. Nitro group reduction, deoxygenation and epimerization complete the synthetic route.
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