An efficient strategy for formation of C-N bond by benzyl chloride over nano α-Fe2O3

Abstract

Nano α-Fe2O3 was prepared using PEG-400 as dispersant by a simple sol-gel method, as proved by XRD, SEM, TEM and ICP-MS. The α-Fe2O3 was demonstrated to be an efficient catalyst for N-benzylation of aliphatic and aromatic amines with benzyl chloride and benzyl bromide in 8% Na2CO3 aqueous solution, achieving ca.100% conversions and >82% selectivity to monosubstituted products for aromatic amines and higher selectivity to disubstituted products for aliphatic amines at 50–80°C and reaction time 1–3h. The catalyst was easily recovered and reused effectively three runs without a significant loss of catalytic activity.