Abstract
An efficient and convenient one-pot two-step process for the regioselective synthesis of the novel tricyclic system 2-chloro-4-methyl-5,6-dihydrobenzo[b]pyrimido[5,4-f][1,4] oxazepine has been described via heterocyclization of 5-(chloromethyl)-2,4-dichloro-6-methylpyrimidine and 2-aminophenol under mild condition followed by reaction with the various secondary amine in moderate to good yields and short time (4a-f).
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