Abstract
It is of great significance to the efficient and convenient synthesis of amides as their great application in medicinal chemistry. However, some problems still exist in the preparation of amides, such as atom-economic. Here, a new and efficient method to prepare amides by the carbonylation of amines was developed without CO gas and palladium catalyst. Mo(CO)6 was employed as carbonyl source, different amines could tolerate the reaction conditions, and the corresponding amides were obtained with good to excellent yields. A possible reaction mechanism was proposed. The method provides a potential way for the synthesis of amides.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
