Abstract
The synthesis via the Mannich reaction of a series of 14- and 15-membered ring mixed donor thiophene-containing macrocycles is reported. The macrocycles each incorporate two oxygen and two nitrogen donor atoms and were obtained in high yields without any requirement for high dilution techniques or metal ion templates. The compounds can be purified by simple recrystallisation. The crystal structure of the 15-membered ring macrocycle C29H32N2O2S2 (4b) has been determined. The structure shows that the bulky benzyl substituents have a major effect on the macrocyclic ring geometry.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Chemical Society, Perkin Transactions 1
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
