Abstract
Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disorder that affects almost every organ system in the body. It has a predilection for non-Caucasian women of child-bearing age and can cause serious complications in many organ systems. Case presentation: In this case, we report a highly atypical presentation of SLE previously healthy 46 year old female. She presented with atypical chest pain and elevated troponin levels concerning for Acute Coronary Syndrome (ACS). During the course of clinical workup, SLE was diagnosed and Lupus Nephritis was found on Kidney Biopsy. She was started on treatment for her SLE and Lupus Nephritis with improvement of her symptoms. Conclusions: This study highlights an interesting variant presentation of SLE and the unique diagnostic and treatment challenges that it posed. Further research into the pathogenesis, prevention, and diagnosis of SLE is warranted and this study aims to promote research into this and other autoimmune conditions.
Highlights
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disorder that affects almost every organ system in the body
Further research into the pathogenesis, prevention, and diagnosis of SLE is warranted and this study aims to promote research into this and other autoimmune conditions
SLE is common diagnosed from 15 to 44 years of age. It is strongly associated with high levels of Antinuclear Antibodies (ANA) with variants of SLE demonstrating additional serologies: e.g. AntiDouble stranded DNA Antibodies and Anti-Histone Antibodies
Summary
This study highlights an interesting variant presentation of SLE and the unique diagnostic and treatment challenges that it posed.
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