Abstract

Botrytis cinerea is a well known pathogen of a number of commercial crops and produces many structurally diverse metabolites. There is no evidence for the production of host-specific toxins by this fungus, which is in accordance with the broad host range of this pathogen. Botrytis produces two series of phytotoxic metabolites: a family of characteristic sesquiterpene metabolites which contain the basic botryane skeleton, principally botrydial and dihydrobotrydial and two polyketide lactones types, botcinins and botrylactone [1,2,3]. The higher production of polyketide toxins from a botrydial sesquiterpene cyclase nock out mutant strain, led us to reinvestigate the structure and biosynthesis of these polyketide compounds.

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