Abstract
Background: The Incidence of Poisoning Is Constantly On The Rise In The Modern World With A GradualShift Towards The Use of Agricultural Poisons In Suicides With Majority of Cases Using OrganophosphateCompounds And In India The Incidence of Ingested Suicidal Poisoning Is High Especially In The SouthernStates. This Study Is Undertaken With A View To Asses If There Is Any Correlation Between Plasma Levelsof Pseudocholinesterase and mortality in cases of acute organophosphate poisoning. Method: The study wasconducted on patients of organophosphate poisoning admitted to Bapuji Hospital (J.J.M. Medical College),Davangere during a period of October 2011 to March 2013. Total number of cases studied were 150. Detailedhistory was obtained regarding the amount of poison, type of poison, quantity of poison, etc from the patientand his/her relatives as well from the police.Clinical examination of each patient was carried out and according to signs and symptoms, the patients weregrouped into 3 grades, mild, moderate and severe according to Dreisbach’s criteria. At the time of admissionpseudocholinesterase was measured. All patients were followed-up for 3 days to know the outcome andresults were compared and analysed.Conclusion: Our study concludes that there is a very good correlation between the levels of plasmapseudocholinesterase and mortality as well as morbidity
Published Version
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