Abstract
Female mice of three inbred strains were trained in a T maze to develop a successive-reversal learning set. After obtaining the set, animals were tested at several delay intervals following a signal to reverse in order to measure the activity of the short-term memory trace. Peak performance occurred within 1 min for A/Js, 1 min for DBA/2Js, and 10 min for CBA/Js. Performance deteriorated to chance levels within 20 min for DBA/2Js, CBA/Js, and A/Js. The results indicate genetic differences in short-term memory for the mouse. Moreover, since subjects from all three strains mastered the learning set, differences in simple conceptual behavior of the three strains were not apparent.
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