An analysis of iron-dextran complexes by Mössbauer spectroscopy and positron annihilation technique

Abstract

Abstract The combination of two modern spectroscopic techniques was used for comparative microstructural analysis of several iron-dextran complexes which were used or elaborated as drugs for treatment of iron-deficiency anemias. Slight variations of the iron electronic and magnetic structure in different iron-dextran complexes were detected by Mossbauer spectroscopy. The differences of iron core structure and size were shown in studied complexes also. Variations of dextran structure were detected by the positron annihilation technique for investigated irondextran complexes. These results were considered with histological and histochemical data for iron-dextran complexes to compare the differences of their microstructural variations and biochemical pathways.