An analysis of epidemiological and clinical data of hemorrhagic fever with renal syndrome in Zibo City, Shandong Province in 2015

Abstract

Objective To analyze the epidemiological and clinical characteristics of hemorrhagic fever with renal syndrome (HFRS), so as to provide a scientific basis for control of HFRS. Method Face to face questionnaires were used to investigate the HFRS patients' basic information, morbidity situation, clinical symptoms, living condition, disease history, exposure history, living environment and burden of the disease in Zibo City in 2015. Results A total of 84 HFRS cases were reported in Zibo City in 2015, 82 cases completed the questionnaire, most of the patients were 40-69 years old, accounting for 75.00% (63/84). Spring and autumn were the two peak incidence. The clinical manifestations were as follows: fever, acute onset, fatigue, headache, flushing, which accounted for 95.12% (78/82), 87.65% (71/81), 84.00% (63/75), 65.38% (51/78) and 60.56% (43/71), respectively. Laboratory test results showed blood platelet in 79.17% (57/72) cases was reduced. All of the HFRS cases had not been suffered from HFRS in the past; 72.84% (59/81) of them lived in rural areas; and 17.28% (14/81) of them had a history of contact with rodents. The median of direct cost for medicine, treatment, and inspection fees was 6 000 Yuan, and the median of indirect expenses was 1 000 Yuan. Conclusion The epidemiological and clinical characteristics of HFRS in Zibo City have changed and there is a trend of infecting older people (> 60 years), clinical manifestations are not typical and the disease burden is heavy. Key words: Hemorrhagic fever with renal syndrome; Epidemiology; Clinical features