Abstract
Here we report the first observation of rapid volumetric heating of polydimethylsiloxane (PDMS) under cyclic loadings at a range of high (∼MHz) frequencies. Based on the finding, we developed a microheater which utilizes the vibration damping of PDMS, the most commonly used material in microfluidics, induced by sound waves generated and precisely controlled by a surface acoustic wave (SAW) microfluidic system. An omni-temperature controllability of the microheater enabled us to perform two-step continuous flow polymerase chain reaction for a billion-fold amplification of 134bp DNA amplicon in less than 45sec.
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call