Amylose and amylopectin contents affect OSA-esterified corn starch's solubilizing efficacy and action mode on hesperetin

Abstract

In order to investigate the solubilization effect and action mode of octenyl succinic anhydride (OSA) modified starches with different amylose and amylopectin compositions on hesperetin (HTN), four OSA-esterified corn starches (OSAS) were prepared using the aqueous phase method. Results revealed that all OSAS could improve the solubility of HTN. OSA-High amylose starch (OSA-HAS) had the best solubility for HTN, nearly fivefold that of free HTN, while OSA-Waxy starch (OSA-WS) had the least solubility for HTN, only twofold that of free HTN. Furthermore, FT-IR, XRD, DSC, and 1H NMR demonstrated the formation of complexes and the interactions between OSAS and HTN in the complexes. The results of DSC revealed that HTN and OSAS formed complexes with greater thermal stability. 1H NMR disclosed that the OSA group in the OSA-HAS complex was actively involved in the interaction with HTN. However, in the OSA-WS complex, the starch backbone reacted more with HTN than the OSA group. This study expanded the knowledge on solubilizing HTN by OSA-modified starch and promoted the development of efficient solubilizing or delivery carriers for HTN, thus contributing to the sufficient utilization of citrus flavonoids.