Abstract
The authors present a nonenzymatic sensor for glucose that has an exceedingly low working potential which makes the sensor highly selective over other electroactive species. The sensor is based on the use of a glassy carbon electrode (GCE) that was modified with a nanoporous PdAuNi alloy (np-PdAuNi). The PdAuNi alloy nanostructure displays enhanced electrocatalytic activity for glucose oxidation (compared to PdNi alloys). The modified GCE enables amperometric sensing of glucose at a typical working electrode potential of 0.0V vs. SCE in solutions of pH13 containing 0.1M NaCl. Response is linear in the 5 to 100μM concentration range, with a 1.7μM detection limit (at an S/N ratio of 3). For higher concentrations deviations from linearity were found. The method is selective and reproducible. The modified electrode was applied to the determination of glucose in human serum. Graphical Abstract Nanoporous PdAuNi alloy with three-dimensional bicontinuous nanosponge architecture was successfully prepared via chemical dealloying. The electrochemical nonenzymatic glucose sensor shows a low working potential, wide linear range, good sensitivity, low detection limit and excellent selectivity.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
