Amperometric Detection of Allopurinol in Flow-Injection Analysis on Electrodes Modified by Carbon Nanotubes and Mixed-Valence Ruthenium and Iridium Oxides

Abstract

Mixed-valence oxides of ruthenium (RuOx) and iridium (IrOx) and a composite based on them (IrOx—RuOx) exhibited catalytic activity for allopurinol oxidation when electrodeposited on the surfaces of unmodified glassy-carbon electrodes and those modified with functionalized single-walled carbon nanotubes (SWCNT). The greatest catalytic effect was observed on the electrode modified with composite IrOx—RuOx—SWCNT. A flow-injection method for amperometric detection of allopurinol at the modified electrode was developed. The analytical signal was linearly dependent on allopurinol concentration in the range 1 10 –6 –5 10 –3 M.