Abstract
This communication describes some of the results which have been obtained in the search for an amoebicidal agent which might replace emetine. Eighty-seven compounds have been synthesized starting from two 4-chloroquinolines with a methyl or anilino group in the 2-position. A number of compounds have been found with an in vitro activity on Entamoeba histolytica slightly inferior to that of emetine.
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More From: Proceedings of the Royal Society of London. Series B, Biological sciences
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