Abstract
The results of glucose estimations in 350 specimens of amniotic fluid in 278 pregnancies are presented. In the control group of normal pregnancies, a gradual decrease from 65.25 ± 12.10 mg. per cent (mean ± 2 S.E.) at 7 to 12 weeks to 28.01 ± 4.41 mg. per cent at 17 to 20 weeks was established. After 20 weeks, the same values persisted up to 32 weeks (23.50 mg. per cent), when these began to decrease to 13.28 ± 4.37 mg. per cent in the thirty-eighth week. In the last weeks of pregnancy, the abrupt fall of the mean values, including the absence of glucose in the forty-second week, was established. In pregnancies with placental insufficiency (intrauterine fetal growth retardation, pre-eclampsia, and postmature pregnancy), significantly lower values were present (p < 0.01), while in diabetic pregnancies significantly higher mean values (p < 0.01) were observed. A significantly higher incidence (p < 0.02) of depressed infants (Apgar score ≤ 7) and infants with acidosis-preacidosis was observed in pregnancies with lowered amniotic fluid glucose concentrations. In pregnancies with decreased estriol excretion and meconium-stained liquor amnii, a significantly lower glucose mean value (p < 0.01, about < 0.02) was evident.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call