Abstract

Dopamine-β-hydroxylase has been purified from human serum. The amino acid composition has been determined and found to be similar to that of the enzyme purified from human pheochromocytoma. Human serum dopamine-β-hydroxylase is a glycoprotein, containing 13.11 g carbohydrates/100 g protein. Individual sugar determinations showed the presence of fucose, galactose, glucose, mannose,N-acetylglucosamine,N-acetylgalactosamine andN-acetylneuraminic acid.

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