Abstract
AbstractAminimides are a new class of surface active agents which have antimicrobial activity. These bipolar compounds have activity against both gran‐positive and yeast organisms. Their activity against gram‐negative organisms is low or absent. The acyl derivatives tested showed maximum activity at chain lengths of C14 and C16. Fatty acid derivatives, shorter (<C14) or longer (>C16), were less active. Unsaturation was an important factor contributing to aminimide activity. Their low toxicity and wide spectrum of antimicrobial activity make aminimides ideal candidates for further investigation.
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