Abstract

Abstract and summaryThe newest member of the aminimide family of surfactants was screened for antimicrobial activity. The present report supports past conclusions that chain lengths of C14 or C16 gave maximum activity to the aminimide derivative. When a number of hexadecane compounds with different polar groups were compared, the aminimide exhibited wide spectrum antimicrobial activity. Although the functional group was important, the length and character of the acyl chain also help to determine antimicrobial activity. A new amide antibiotic, Cerulenin, with a 4‐keto‐2‐enyl chain, was more active than the unsaturated isomer. Thus, both the functional grup as well as the chain length contribute to biocidal activity.

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