Amides, Fatty Acid

Abstract

AbstractFatty acid amides, which contain a saturated or unsaturated alkyl chain derived from a fatty acid, can be divided into three categories. The first is primary monoamides in which R is a fatty alkyl or alkenyl chain of C5–C23and\documentclass{article}\usepackage{amssymb}\pagestyle{empty}\begin{document}${{\rm{R}}{^{{\prime}}}={\rm{R}}={\rm{H}}}$\end{document}. The second is substituted monoamides, including secondary, tertiary, and alkanolamides in which R is a fatty alkyl or alkenyl chain of C5–C23; R′ and R″ may be a hydrogen, fatty alkyl, aryl, or alkylene oxide condensation groups with at least one alkyl, aryl, or alkylene oxide group. The third category is bisamides where R groups are fatty alkyl or alkenyl chains. R′ and R″ may be hydrogen, fatty alkyl, aryl, or alkylene oxide condensation groups. Primary and secondary amides show strong hydrogen bonding which accounts for their high melting points and low solubilities in most solvents. With tertiary amides (disubstituted amides), hydrogen bonding is not possible, as exhibited by their increased solubility and lower melting points. Many fatty acid amides are essentially insoluble in water. Amides have a strong tendency to reduce friction on various surfaces by forming a layer on surfaces. This coating action may be attributed to their hydrophobic character and strong hydrogen bonding. Primary, secondary, and bisamides are widely used as lubricating or slip agents and alkanolamides are commonly used as surfactants Amides in general are stable to elevated processing temperatures, air oxidation, and dilute acids and bases. The dehydration of amides which produces nitriles is of great commercial value. The most widely used synthetic route for primary amides is the reaction of fatty acid with anhydrous ammonia. Most monosubstituted and disubstituted amides can be synthesized with or without solvents from fatty acids and alkylamines. Most bisamides are prepared by the reaction of the primary fatty amide and formaldehyde in the presence of an acid catalyst, or by the reaction of ethylene diamine with fatty acid. Some primary fatty amides available from various manufacturers under different trade names are coco fatty amide, stearamide, hydrogenated‐tallow fatty amide, docosanamide, octadecenamide, and 13‐docosenamide.. Many substituted fatty acid amides are commercially available, but other, specialty substituted amides are of lower commercial volume.