Abstract
Abstract Rationale: Ameloblastic fibro-odontoma (AFO) is a rare mixed odontogenic tumour with a preferential location in the posterior mandible and with a variety of radiological aspects. We report two clinical cases of AFO in two rare locations and with unusual radiological aspects. Patient Concerns: The first patient is a 37-year-old female with an asymptomatic intraoral swelling located in the anterior mandibular. The second patient is a 16-year-old girl with a chief complaint of missing maxillary canine. Diagnosis: Both cases were diagnosed with AFO. Treatment: For the first patient, a biopsy was performed, and for the second one, the lesion was surgically excised. Outcomes: The first patient is under regular surveillance and the other was followed up for one year without any evidence of recurrences. Take-away lessons: Despite many efforts, the nature, histology and therapy of these lesions remain very confusing.
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