Abstract

Ameloblastic fibrodentinoma (AFD) is a rare benign odontogenic tumor, which can mislead the clinician to a variety of differential diagnosis. A 5-year-old white man presented with a painless swelling of the left maxillary region of 1-year duration. A cone beam CT revealed a hypodense unilocular lesion with well-delimited borders involving the impacted upper molars and the left tuberosity region. Differential diagnoses of adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, ameloblastoma, and ameloblastic fibroma were considered. After incisional biopsy, the histopathologic sections showed fragments of connective tissue containing islands and cords of odontogenic epithelium with peripheral cells resembling ameloblasts. The lesion was surgically removed, and the histopathologic examination showed deposition of dentinoid material in contact with the islands of odontogenic epithelium. A diagnosis of AFD was made. Currently, the patient is under observation and without recurrence.

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