Abstract

A new oral carbenicillin indanyl ester was compared with ampicillin and cephaloglycin in the treatment of 251 male patients infected with 271 bacterial strains. There was no significant difference in the efficacy of carbenicillin and ampicillin, but both showed significantly higher rates of cure and lower rates of reinfection than cephaloglycin in the follow-up period. Oral carbenicillin was effective in 50% of the 20 patients with infection due to Pseudoinonas. It is concluded that most urinary-tract infections, including those caused by Pseudomonas, can be treated on an outpatient basis with oral carbenicillin.

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