Abstract
We evaluated the effects of combining a porous poly(l-lactide-co-e- caprolactone)/ß-TCP membrane with a bFGF incorporating -gelatin sponge on bone regeneration in mandibular ridges. Dome-shaped membranes and the gelatin sponges were implanted in full-thickness saddle-type defects created in mandibular alveolar ridges of beagles. Three and 6 months later, bone regeneration was examined by soft X-ray, micro-CT, pQCT, and histologically. New-bone volume and density were higher in the experimental group than in the control.
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