Abstract
Abstract Background: Despite the measures taken to the traditional risk factors for pressure injury (PI), there is still a great residual risk. Therefore, on the basis of managing traditional risk factors, it is necessary to find and interpret interventionable factors for predicting and treating PI. Objective: To investigate the relationship between serum transferrin level and the severity of PI. Methods: PI patients from The Affiliated Hospital of Qingdao University between July 2020 and June 2021 were selected as the case group, which was further divided into stage 1 (30 patients), stage 2 (59 patients), stage 3 (64 patients), and stage 4 (43 patients) according to PI stage. The control group consisted of 196 bedridden patients of similar age who did not have a PI and were matched to the cases by sex and age. This study evaluated the serum transferrin level between the case and control groups. Results: The serum transferrin levels were statistically significant between the control and case groups (P<0.001). The serum transferrin level of PI patients with stages 3 and 4 was significantly lower than that of patients with stages 1 and 2 (P<0.05). After adjusting for covariates, serum transferrin remained negatively associated with PI occurrence (B=−0.045, adjusted OR=0.956, P<0.001) and stage (B=−2.266, adjusted OR=0.104, P<0.001). Conclusions: The serum transferrin level was decreased with the progression of PI. This study suggests that serum transferrin can serve as positive evidence for treating PI patients.
Published Version
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