Abstract
Most studies have either excluded patients using contact lens or not taken their effect while analyzing post-collagen cross-linkage (CXL) changes. This study aims to study impact of CXL on lens fit in both quantitative and qualitative manner. To evaluate changes in CL fit post-CXL and to correlate these changes with alterations in corneal topographic parameters. Prospective intervention study on 20 keratoconic eyes of 14 patients (age>18years), with mean follow-up of 6months. Preoperative evaluation included UCVA, BCVA, corneal topography, AS-OCT and contact lens fit. Patients were evaluated at 2weeks, 1, 3, 4 and 6months post-CXL; contact lens trial with standard rigid gas permeable (RGP) lens performed at 3 and 6months. Changes in objective and subjective parameters of lens fit. Over 6-month follow-up post-CXL, improvement in visual acuity by one Snellen line, both UCVA and BCVA, and decrease in flat/mean/apical K by 0.8D, 0.8D and 1.3D, respectively, resulted in significant improvement in RGPCL fit. Almost 20% increase in near-ideal fit, 100% acceptable fit, 65% improved subjective comfort with 8h/day increase in duration of comfortable CL wear were observed. Despite no statistically significant change in objective parameters of lens fit, a tendency for flatter lens fit along with contact lens induced further flattening of the ectatic cornea which resulted in marked improvement in both objective and subjective contact lens fit.
Published Version
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