Abstract
Homologous chromosome pairing is known to be an essential point in the meiotic process, because it allows interchromosomal exchanges (crossovers) to occur in a balanced way. Interactions between homologous loci has been shown to occur in somatic cells of plants and animals. In general, somatic pairing is less extensive than in the germ cells. Although their functional significance remains unclear, recent observations show that homologous interactions are more widespread than previously thought. It has also become apparent that imprinted chromosomal regions can be involved in homologous pairing in mammalian somatic cells. This chapter will focus on the description of long-range homologous interactions and their implications in the conrext of imprinted chromosomal regions.KeywordsImprint GeneReplication TimingHomologous PairingMonoallelic ExpressionChromosomal DomainThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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