Abstract

AbstractModification of the chitosan chemical structure by grafting hydrophobic fragments makes it possible to synthesize derivatives with amphiphilic properties. These derivatives were used as emulsifiers in the aqueous phase during the production of polylactide microparticles via the oil/water solvent evaporation technique. The application of the derivatives allows to achieve a high yield of the microparticles and to provide a hydrophilic coating on the surface of polylactide microparticle. The chitosan‐coated polylactide microparticles were analyzed in terms of mean size, size distribution, surface, and internal morphology. The ability of the obtained microparticles to be used as a starting component for the fabrication of 3D materials through the surface‐selective laser sintering was evaluated, and the optimal parameters for the process have been determined.

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