Abstract
An investigation into the alkaloidal content of the bulbs of the Amaryllidaceae species, Crinum variabile (Jacq.) Herb., was performed for the first time and led to the isolation of 8 known alkaloids, namely: lycorine, 1,2-O-diacetyllycorine, 1-O-acetyllycorine, 2-O-acetyllycorine, haemanthidine, 6-epihaemanthidine, bulbispermine and criwelline. It should be noted that a “full set” of lycorine and its acetylated derivatives (1,2-O-diacylated, 1-O- and 2-O-monoacylated) were obtained from the C. variabile bulbs, with lycorine being obtained in significant amounts (0.80% of dry bulb mass, i.e., 8.0 g/Kg C. variabile dry bulb mass).
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