Abstract
Tayanc-Prasad Syndrome is characterized by geophagia, iron defi ciency anemia, hepatosplenomegaly, skin changes, hypogonadism, and retardation of growth and development. A 13.5 year-old female patient who had geophagia for approximately 5–6 years, presented with an ongoing diarrhea 3–4 days a week for the last 4–5 years, headache, loss of appetite, palpitations, and pallor for one year. The patient had an iron defi ciency anemia, and low levels of ALP (alkaline phosphatase) and IGF-1 (insulin-like growth factor-1). The patient was treated with ferroglycine sulfate and zinc sulfate. After the 6 month follow-up, there were an increase in height of approximately 2 cm, a weight gain of 6.7 kg, a chest girth increment of 5.5 cm, and an increment of the upper mid-arm circumference of 4 cm. The hepatosplenomegaly disappeared. Anemia and ALP level improved signifi cantly. As a result, zinc defi ciency should be suspected in a patient with iron defi ciency anemia, low ALP levels, as well as geophagia. Although decreased levels of zinc, ALP and IGF-1 were detected in this particular case, more research is required in a larger number of patients.
Published Version
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