Abstract
To the Editor.— The use of disulfiram (Antabuse) as an adjunct to alcoholism treatment programs is well known in this country, and may be increasing. 1 The minimal dose of alcohol necessary to evoke a reaction in the disulfiram treated patient is somewhat controversial, 2 although it has been suggested that as little as 7 ml of alcohol may cause typical reactions. 3 Thus, in disguised forms, alcohol could represent a serious hazard for patients receiving disulfiram. Our experience with a patient who had a disulfiram-alcohol reaction following the ingestion of a single dose of an over-the-counter, widely advertised cough medication, containing 25% alcohol, serves to emphasize the dangers of alcohol-containing preparations in these unique patients. Report of a Case.— The patient, a 46-year-old white man, was admitted to the hospital because of the abrupt onset of nausea, vomiting, and flushing of several hours' duration. He had been a heavy
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