Akut Pankreatit Hastalarında Nötrofil/Lenfosit ve Trombosit/Lenfosit Oranlarının Tanısal ve Prognostik Değeri

Abstract

Objective: In this study, we aim at demonstrating whether we can use neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratios (PLR) as a parameter in monitoring the disease severity of Pancreatitis Patients. Materials and Methods: A total of 200 patients diagnosed with acute pancreatitis, hospitalized and monitored in gastroenterology service, whose files had retrospectively been studied, were included in the study. The severity and prognosis of acute pancreatitis were evaluated with the Atlanta classification. Results: The average of NLR was 9.84±9.60 in the patient group but 2.00±0.86 in the control group. The NLR level was found higher in the patient group. The cut-off value was found as 2.85 (Sensitivity: 86% and specificity: 81%). Although no significant change was found in terms of the average of NLR concerning the disease severity, the decrease in the average of NLR among the groups was found significant in 48 hours. Conclusion: We have found that only the change in NLR level in the first 48th-hour could be associated with the disease severity. We found NLR as a parameter that can be used, applied, and accessed easily.