Abstract
ABSTRACT
 Breadfruit leaves (Artocarpus altilis) was contain compound of flavonoids, tannins and phenol that
 the ability as antibacterial against Staphylococcus aureus bacteria. The extracts of breadfruit
 leaves formulated became ointment that made practice to used. The combine of ointment bases can
 obtain of good consistency like the combine of adeps lanae with vaselin album and cera flava with
 vaselin album. The aims of this study to know the profile of antibacterial activity of the breadfruit
 leaves extract ointment with two kind of the combine of ointment bases. The breadfruit leaves
 extract has obtained by maceration method used etanol 70% solvents. The breadfruit leaves
 ointment was made by melting method with combination bases A is adeps lanae:vaselin album as
 F1 (13.5%:76.5%), F2 (45%:45%) dan F3 (76.5%:13.5%), while combination B is cera
 alba:vaselin album as F1 (85.5%:4.5%), F2 (81%:9%), F3 (76.5%:13.5%). antibacterial activity
 assay was used well diffusion method and analyzed descriptively. The research result that the all
 formulas has breadfruit flavor, smooth texture and brown color. Two variatons of combination
 bases ointment has antibacterial activity against Staphylcoccus aureus bacteri with formed of
 inhibition zone around the well.
 Keywords: Breadfruit leaves extract, ointment, antibacterial, combination of ointment bases
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