Abstract
An attempt has been made to explore the interrelationship between the age-related changes in acid mucopolysaccharides (AMPS) and water content of the renal papilla. Water content of human renal papilla changes significantly with age but the correlation between AMPS and water content of this region is just below the 5% level. On the other hand, the ratio of water content to AMPS decreases significantly with advancing age. Since the change in the ratio of these two substances is interpreted to express mainly the alteration of the ground substance with age, the possibility is discussed that the age-related changes in AMPS and water content of the renal papilla might be related to the decrement in concentrating ability of urine in the elderly person.
Published Version
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