Abstract
The nuclei of cells from the supraoptic nucleus (SON) of virgin female C57BL/lcrfat mice, ranging from eight to thirty-two months of age, were studied by electron microscopy. A quantitative study has shown that the frequency of membranous and fibrillar inclusions within the cell nuclei increase with age, but the membranous inclusions decline at extreme age, (32 months). Inclusions of either type were rarely encountered in young or old male mice.
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