Abstract

• ASFV MGF360-13L is a negative regulator by controlling cGAS-STING signaling pathway. • ASFV MGF360-13L suppresses the cGAS-STING-IFN-I axis by degrading STING. • ASFV MGF360-13L is likely to mediate the degradation of STING through the autophagic pathway.

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