Abstract
This paper describes the characteristics of 156 children and adolescents with hypopituitarism from 2 hospitals in Sudan Congenital causes (86.5%) were more prevalent than acquired causes (13.5%) Consanguinity was found in 77.8% of patients overall and 91% of patients with congenital aetiologies. There were six family clusters with multiple pituitary hormone deficiencies and three families with isolated growth hormone deficiency
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