Advantages of high fiber content millet family chosen for the study of anti-hyperlipidemic activity using the extract of Italica seeds and husk on rats

Abstract

Setariaitalica is usually identified as Foxtail millet (Korralu in Telugu). It belongs to the millet family consisting of high fiber content along with many minerals, vitamins, essential aminoacids, proteins, gluten-free and very less quantity of carbohydrates. Due to enormous advantages and was less explored, this millet was chosen for the study of antihyperlipidemic activity. To examine the anti-hyperlipidemic activity of hydroalcoholic extract of seed and husk of Setariaitalicain aetherogenic diet-induced hyperlipidemic rats. The hydroalcoholic extract of Setariaitalica seeds and husk are assessed for antihyperlipidemic movement in atherogenic diet brought hyperlipidemic rats. The study was performed by comparing the results with that of standard drug atorvastatin (10mg/kg body wt). The education results are uttered as mean ± S.E and the data is analyzed by utilizing one-way investigation (ANOVA). Values with P<0.05 is measured as important. Oral management of 500mg/kg body wt of hydroalcoholic extract of Setariaitalica showed a significant reduction in the serum levels of low-density lipoproteins (LDL), triglcerides (TG), total cholesterol and an increase in high-density lipoproteins (HDL) than the standard control. The Hydroalcoholic extract of seed possesses significant activity than the hydroalcoholic extract of a husk of Setariaitalica. The hydroalcoholic seed extract of Setariaitalica produced promising results the millets have to be consumed as a diet as it immensely controls the serum cholesterol levels, which plays a vital role in the control of cardiovascular diseases.