Advancing Uterine Cancer Care: Transvaginal Ultrasonography in Preoperative Staging Analysis

Abstract

Objective: To determine the role of transvaginal ultrasonography in the preoperative staging of uterine cancer. Methods: The research included 110 women who had been diagnosed with endometrial malignancy by histological confirmation, whichwas achieved through procedures such as dilation and curettage, hysteroscopy, or endometrial biopsy. Additionally, women who had ahigh suspicion of endometrial malignancy based on imaging results and were scheduled for surgery as their main therapy were alsoeligible to participate in the study. Results: A total of 110 individuals satisfied the criteria for inclusion in the research, with an average age of 49.89 ± 2.99 years. In relation to the extent of myometrial invasion, our study yielded sensitivity rates of 81%, 81%, and 69% for the subjective, Gordon, and Karlssontechniques, respectively. The corresponding specificity rates were found to be 67%, 60%, and 81% for the same approaches. The subjective, Gordon, and Karlsson techniques yielded corresponding overall accuracies of 74%, 70%, and 75%. The use of contrast-enhanced MRI yielded a sensitivity, specificity, and overall accuracy of 94%, 72%, and 84%, respectively, in the assessment of myometrial invasion. In the assessment of cervical stromal invasion, the ultrasound subjective technique showed a sensitivity of 33% and a specificity of 99%. On the other hand, the objective method yielded a sensitivity of 52% and a specificity of 92%. The total accuracy for both methods was determined to be 90% and 83% respectively. The use of contrast-enhanced MRI yielded a sensitivity, specificity, and overall accuracy of 69%, 100%, and 96% respectively in detecting cervical involvement. Conclusion: We concluded that the utilisation of pelvic ultrasound in the preoperative staging of endometrial cancer holds significantvalue. It demonstrates a notable sensitivity in evaluating myometrial invasion, exhibiting a reasonable to moderate level of concordancewith MRI. Furthermore, it exhibits a superior, albeit still moderate, level of agreement with MRI in assessing cervical invasion.