Abstract

Caries is the most common and extensive oral chronic disease. Due to the lack of anti-caries properties, traditional caries filling materials can easily cause secondary caries and lead to treatment failure. Nanomaterials can interfere with the bacteria metabolism, inhibit the formation of biofilm, reduce demineralization, and promote remineralization, which is expected to be an effective strategy for caries management. The nanotechnology in anti-caries materials, especially nano-adhesive and nano-composite resin, has developed fast in recent years. In this review, the antibacterial nanomaterials, remineralization nanomaterials, and nano-drug delivery systems are reviewed. We are aimed to provide a theoretical basis for the future development of anti-caries nanomaterials.

Highlights

  • Caries is one of the most important diseases, which has seriously threatened human oral health, and even the whole body, for a long time [1]

  • When NAg was added to the adhesives, its antibacterial property increased significantly, but whether it had any effect on the bonding strength is still controversial

  • The results showed that NAg could significantly inhibit the growth of Streptococcus mutans and Lactobacillus on the composite surface [13]

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Summary

Introduction

Caries is one of the most important diseases, which has seriously threatened human oral health, and even the whole body, for a long time [1]. Caries treatment is still based on filling restoration. Clinical studies showed that dental filling and bonding materials’ lack of anti-caries properties could result in a high incidence of secondary caries. The development of new anti-caries materials is a hot spot in the field of caries prevention and treatment. The smaller the diameter of nanoparticles, the larger the specific surface area, and the stronger mechanical properties and antibacterial effect [5]. They can be used as the carrier of antibacterial drugs since nanoparticles have the characteristics of targeting antibacterial with. Nanotechnology has shown great application prospects in the development of anti-caries materials, especially in nano-adhesive and nano-composite resin. We are aimed to provide the theoretical basis for the future development of anti-caries nanomaterials

Metal Nanoparticles Used in Caries Infections
Other Metal Nanoparticles
The Anti-Caries Mechanism of Mental Nanoparticles
Remineralized Nano Anti-Caries Materials
Remineralization Mechanism of Nanoparticles
Nanodrug Delivery System
Liposomes
Dental Caries Vaccine
Biomimetic Nanocatalyst
Findings
Conclusions
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