Abstract
The pathogenesis of vitiligo remains unclear,and it may be closely related with hereditary factors.It is proposed that vitiligo is consistent with a model of polygenic inheritance.Studies have mapped vitiligo-associated genes to chromosome 1p31(AIS1),7q(AIS2),8p(AIS3),17p(SLEV1)and 4q13-q21 (AIS4).Additionally,many susceptibility loci have been discovered for vitiligo,including human leukocyte antigen gene,PTPN22 gene,VIT1 gene,catalase gene,TAP1,angiotensin-convertion enzyme gene,glutathione S transferase gene,interleukin-10 gene,etc. Key words: Vifiligo; Chromosome mapping; Heredity
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Schedule a callMore From: International Journal of Dermatology and Venereology
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