Abstract

Adrenocortical carcinoma is a malignant endocrine tumor. There is no unified standard for diagnosis and treatment because of the low incidence. There are two peaks in the age of onset, which are 0 to 10 years and 40 to 50 years, and the incidence of children and women is higher. The percentage of 60 to 70 ACC patients show clinical symptoms due to the excess hormone, but there are still many patients with poor clinical symptoms. The common endocrine symptoms include polycythemia, masculinity or male breast development. The prognosis of ACC is poor, and the classification and staging of the tumor and hypercortisol are associated with the prognosis. Surgical resection is the first choice, but the recurrence rate of the tumor is high and the overall survival rate is low after operation. In this paper, the clinical characteristics, diagnosis, differential diagnosis, prognosis and treatment of ACC are summarized by reviewing the past researches. Key words: Therapeutic used; Review; Surgical procedures, operative; Adrenocortical carcinoma; Clinical features

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