Advances in preservation of endocrine function with ovarian tissue cryopreservation and transplantation in cervical cancer.

Abstract

The incidence of cervical cancer ranks the first among the gynecological malignant tumors. Given the implementation of widespread cervical cancer screening and the improvement of clinical treatment, the cervical cancer mortality has decreased substantially. However, surgery, radiotherapy, and chemotherapy may impair the ovarian function, resulting in premature ovarian insufficiency and premature climacteric, which has reduced the quality of life in young patients. As a new fertility preservation technology, autologous ovarian tissue cryopreservation and transplantation is developing rapidly and showing great potentiality in preserving ovarian endocrine function of young cervical cancer patients.