Abstract
Alopecia areata (AA) is an autoimmune disease affecting the anagen-stage hair follicles, and is triggered by internal or external factors. It has been revealed that cytokines and some small molecules play essential roles in the development of AA. Interferon (IFN)-γ, interleukins and tumor necrosis factor-α are common cytokines involved in the pathogenesis of diseases. Monokine induced by IFN-'γ, IFN-γ inducible protein 10, B cell activating factor, HLA antigens, as well as stress hormones play certain roles in the development of AA. Within the scope of this paper, the authors attempt to summarize the complexity of etiology of, underlying mechanisms of and possible treatment options for AA. Key words: Alopecia areata; Cytokines
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