Advancements in the research of combining MRI and CRISPR technology for the treatment of breast cancer

Abstract

Cancer remains a significant contributor to global mortality, posing a considerable public health challenge. Among the various types of cancer, breast cancer stands out as one of the most prevalent among women worldwide. Ongoing efforts are dedicated to the development of innovative treatments with minimal side effects. A groundbreaking genome technique for editing, CRISPR-associated protein-9 (Cas9), also known as clustered regularly interspaced short palindromic repeat (CRISPR), has become an effective instrument for genetic modification. This technology has revolutionized genome editing across diverse biological fields, including its applications in genome therapy and tumor research. With ongoing advancements in sensitivity, specificity, and diagnostic accuracy, magnetic resonance imaging (MRI) has gained increasing recognition for the detection of breast cancer. MRIs capability to produce high-resolution images plays a pivotal role in aiding healthcare professionals in precise localization of breast masses, tumors, and other abnormalities. Additionally, it facilitates the assessment of parameters like tumor size, extent, and lymph node involvement, contributing to the formulation of more accurate treatment strategies. Here is a review summary of the combined utilization of MRI and CRISPR technology in breast cancer treatment. It explores the synergy between these two technologies, discussing their advantages and disadvantages and their potential to enhance diagnostic and therapeutic outcomes.